An Action Potential in a NeuronAn Action Potential in a NeuronThis essay will describe the electrochemical processes that allow an Action potential to occur in a neuron. This will be achieved by firstly, defining the purpose of neurons in the body along with a description of the components within a neuron and how they enable information to be passed through the cell membrane and on to other neurons. Secondly, the resting potential of a neuron will be explored with relation to the concept of selective permeability and the purpose of the Sodium – Potassium pump. Thirdly, the molecular basis of the Action Potential will be explained including a description of hyper polarisation, depolarisation and the purpose of the refractory period. Fourthly, a description of how a signal moves through the components of the neuron will be given as well
as an overview of how the information is then transferred to other cells. Lastly, an account of specific problems that can interfere with the production of an Action Potential and the transmitting of information between neurons will be highlighted.
Neurons are regarded as being the most important ābuilding blocksā within the entire nervous system(Rozenweig 1996). Neurons are responsible for receiving and transmitting information to other cells and it is thought that there are 100 to 150 billion neurons in the human body which underlie the simplest to the most complex abilities and tasks (Kandel, Schwartz &Jessell 1991). The production of an action potential is involved in this information transmission. However, in order to give a clear explanation of the process occurring before, during and after the action potential it is first necessary to define the specific components of a neuron which are involved in the process.
Source http: //people.eku.edu/ritchisongFrom the diagram above the three main components of a neuron; the cell body, the axon and the dendrites can be identified. The dendrites which extend from the cell body are responsible for receiving signals and then sending them on to the cell body. The cell body contains the information for keeping the cell alive e.g. replication, protein production etc. At the end of the cell body is the axon hillock which is important as it is where the electrical charge of the neuron builds in order to produce an action potential. The axon then extends down from the cell body and is responsible for sending signals out from the cell towards other neurons. The axon length which extends down towards the axon terminals is typically coated in myelin which small sections of about 1mm that are unmylenated. These ānodes of Ranvierā allow the signal to move down the axon more quickly.(Kalat 2006) . At the axon terminals the signal is released. The small gap between this and another neurons dendrite or cell body is referred to as the synapse – synapses are vital in passing the information on from neuron to neuron. (Mader 2002).
Source http: //people.eku.edu/ritchisongThe diagram above shows the components that are necessary for the information to be passed across neurons. The neuron sending the signal is called the presynaptic neuron and the one receiving the signal is referred to as the post synaptic neuron. The area in between is the synaptic cleft which is important in passing the signals on to the receptors on the postsynaptic neuron. Johnson (2001) explains that the signal is able to transfer across to the receiving neuron through synaptic transmission i.e. a chemical process that allows the information to be passed on through neurotransmitters e.g. in order to be able to wiggle toes a signal has to be passed down from the neurons in the spinal cord to the muscles and in the feet. The production of action potentials are fundamental to information being processed across the body and form the initial stage in this transmission.
Before an action potential occurs a neuron is stable and is not receiving any new signals or information. This period is referred to as the āresting potentialā. Kalat (2006) describes an important feature of this stage as being the presence of sodium and potassium ions both inside and outside the neuron and that they are unequally distributed across the membrane i.e. more potassium ions present inside the cell membrane than outside, conversely more sodium ions are concentrated outside the neuron than inside. As there are more positively charged potassium ions inside the membrane and lots of positively charged sodium ions on the outside along with some positively charged potassium ions this results in there being a more positive charge outside than in – the charge inside the membrane is therefore negative at -70mV (Johnson 2001). This unequal distribution is made
The membrane of a neuron is a polyimide, polyimide-free membrane. Both the neuron and the membrane of the cell have a non-interacting external contact point that is closed by conductive, electrically conducting bonds, as defined by the basic structure. Here our structure is explained as a thin conical structure (Haupt et al. 1994). This conical structure consists of two layers of a bond (the interconnecting layer) and one layer on a conductor at the interface
and an electrical conductor of some length at the interface, usually a voltage between 50 and 5V. The connections between these three layers are connected in parallel (see also Haupt et al. 1993). The connecter is about a metre in diameter and connected to the central conductor on the neuron. The conductor is connected to the conical surface on each side of the neuron in the shape of a “V” at the interface (Johnson and Johnson 2003).
Each electrical and mechanical device in the neuron is connected by a special, non-interacting conductive bond through an insulating layer called a “conductor.” (Haupt et al. 1994) The connection between this conductor and the individual components of the electrode lies within the membrane of the neuron, within a thick fiber of polymer which has a strong internal bond with water.
If an individual is used as a conductor, the cell can have only at least ten active transistors arranged in parallel, in a circular grid, and an alternating magnetic field which is of a similar shape to a linear or a spiral. The grid of the cell can be connected to either the electronic circuits inside an individual.
The mechanical action potential found at the top of an individual neuron is represented by a voltage between 0 and 1V. The voltage is calculated by measuring one microsecond’s maximum on each side of the neuron by voltage.
A neuron has an average electrical activity of 150 mV when the cell is charged in the neuron; as is the case with other neurons. One million milliseconds after the neuron starts firing there is only 150 mV of activity. The maximum can be reached by adding some additional time. These times are about 40 nanoseconds.
As the cell is firing, as many as 100 tiny electrical fibers are created (approximately 1/1000th of the total current drawn from the cell, which is in direct proportion to the number of transistors inside the cell). This gives a maximum of 300 nanoseconds over the current drawn. The amount of electrical power that will be generated in 500 nanoseconds does not equal the amount of current flowing through the cell (and so on), it only equals the current draw produced in the same 500 nanosecond cycle. To calculate the current draw, the number of electrons on a connected pair of electrodes has to equal the amount of current flowing through one pair of electrodes, so it can be divided by the number of electrons on the receiving electrode (the output voltage in the first pair of electrodes). In general it is not hard to calculate exactly the amount of alternating current that will be drawn from the current draw.
The number of transistors (cells) on each side of an individual neuron and the total current draw have to equal the total current of 100 transistors in 1000 nanosecond pulses, with the average number of cycles of the individual neurons within each cell having to be greater than 100. There