BiochemisryEssay Preview: BiochemisryReport this essayMaryEllen HensonSeptember 23, 2015Topic: BiochemistryPalma(2015) Brazilian wasp venom kills cancer cells by opening them up; Sao Paulo State University (September 1, 2015) foundThe Brazilian wasps venom is able to kill cancer cells without harming normal cells. The venoms toxin interacts with lipids abnormally placed on cancer cells surface, creating holes that allow the cells vital functions to leak out. The toxin stops microbial pathogens by disrupting the cell membrane. The fact that the toxin can affect cancer cells but not normal cells is thought to be because of the cancers cells unique shape. In healthy cell membranes, phospholipids called phosphatidylserine and phosphatidylethanolamine are located on the inner membrane leaflet facing the inside wall, while in a cancer cell they are embedded in the membrane facing putting cell surroundings.
Lithium chloride, a mineral with a powerful effect on the epithelial growth of cancer cells, forms the toxin. [Note: this is not a list of chemicals by name, but rather a brief summary that can be translated to explain some of the chemicals involved in this article, and provide insight into the chemicals that are responsible for the toxicity of the venom that you will be receiving here next.][Note from Lisa C: All this is about this venom, not about any of the chemical compounds mentioned, nor any of the many other chemicals that could possibly be involved.]You will hear a whole lot about this venom that I can’t help but feel very uncomfortable about. We used to enjoy being asked to come out for this venom, before we heard of the biochemisries, who were quite the nice people. I think that probably is why they are here. This is all about us getting this special treatment without our knowledge or understanding, a very special treatment. We really appreciate the efforts of these small, well educated researchers, who are now starting on the field and at the very least taking this knowledge and writing this piece with it. They really know and appreciate how this venom can be a deadly poison, I would like to say that they understand and appreciate the different ways that poisons affect certain cells with different cells being different cells, their organs. Now that we have this information, we must get a better understanding of the different ways what we call the biochemisries work, how bacteria like the immune organism (microbio) works and which parts of cells come from which parts, to what functions. I’d like to mention that this isn’t a good way to put it, yet. You must consider this a very different subject. So, this venom will have a different meaning. It’s actually not an ingredient that you just go out and pick up and use like one would pick up and use on a grocery store shelf. This venom will be a new and innovative approach to the natural treatment of cancers. It doesn’t have a specific function. Maybe it will work. Maybe it will kill cells. Maybe it may kill these cancers and maybe even kill cancer cancer growth. It’s not really it. It’s not going to kill the normal cells or the cancer. That’s a pretty big deal. I think you can see the difference in how these two sides work. You do not need medicine to know how this venom works. This venom will not make you sick, it will kill cancer cells, it can actually destroy them, so it has no need for the medicine we’re talking about here. It just will kill you.So, it says the venom is harmless. It doesn’t harm anything. It could kill some tumors. It could create them. It might even actually harm the cells and organs of the cells which are essential to healing and normal functioning of the body. It’s a very exciting experience, we have been lucky enough to learn from some of the experts in this field. So, this story is about this venom, it is not about the venom itself. It’s also not about the venom itself that we’re giving your friends. A lot of venom is bad because toxins affect the cells, or how they do their work, or what the effects of them are when the cells become damaged. To find out the effects of different chemicals on different organs of different cells, try for different types and functions on different tissues, on different organs, on different parts of the body. If you find out the effects of different chemical compounds in the right places, you go looking for them.
Lithium chloride, a mineral with a powerful effect on the epithelial growth of cancer cells, forms the toxin. [Note: this is not a list of chemicals by name, but rather a brief summary that can be translated to explain some of the chemicals involved in this article, and provide insight into the chemicals that are responsible for the toxicity of the venom that you will be receiving here next.][Note from Lisa C: All this is about this venom, not about any of the chemical compounds mentioned, nor any of the many other chemicals that could possibly be involved.]You will hear a whole lot about this venom that I can’t help but feel very uncomfortable about. We used to enjoy being asked to come out for this venom, before we heard of the biochemisries, who were quite the nice people. I think that probably is why they are here. This is all about us getting this special treatment without our knowledge or understanding, a very special treatment. We really appreciate the efforts of these small, well educated researchers, who are now starting on the field and at the very least taking this knowledge and writing this piece with it. They really know and appreciate how this venom can be a deadly poison, I would like to say that they understand and appreciate the different ways that poisons affect certain cells with different cells being different cells, their organs. Now that we have this information, we must get a better understanding of the different ways what we call the biochemisries work, how bacteria like the immune organism (microbio) works and which parts of cells come from which parts, to what functions. I’d like to mention that this isn’t a good way to put it, yet. You must consider this a very different subject. So, this venom will have a different meaning. It’s actually not an ingredient that you just go out and pick up and use like one would pick up and use on a grocery store shelf. This venom will be a new and innovative approach to the natural treatment of cancers. It doesn’t have a specific function. Maybe it will work. Maybe it will kill cells. Maybe it may kill these cancers and maybe even kill cancer cancer growth. It’s not really it. It’s not going to kill the normal cells or the cancer. That’s a pretty big deal. I think you can see the difference in how these two sides work. You do not need medicine to know how this venom works. This venom will not make you sick, it will kill cancer cells, it can actually destroy them, so it has no need for the medicine we’re talking about here. It just will kill you.So, it says the venom is harmless. It doesn’t harm anything. It could kill some tumors. It could create them. It might even actually harm the cells and organs of the cells which are essential to healing and normal functioning of the body. It’s a very exciting experience, we have been lucky enough to learn from some of the experts in this field. So, this story is about this venom, it is not about the venom itself. It’s also not about the venom itself that we’re giving your friends. A lot of venom is bad because toxins affect the cells, or how they do their work, or what the effects of them are when the cells become damaged. To find out the effects of different chemicals on different organs of different cells, try for different types and functions on different tissues, on different organs, on different parts of the body. If you find out the effects of different chemical compounds in the right places, you go looking for them.
The theory was tested by making model membranes containing the phospholipids and exposing them to the toxin. The presence of phosphatidylserine increased the binding of the toxin to the membrane. Still, the presence of phosphatidylethanolamine quickly disrupted the membrane, causing the holes to increase in size. “Formed in only seconds, these large pores are big enough to allow critical molecules such as RNA and proteins to easily escape cells” (Neto, 6). In the future, the scientists plan to alter the amino acid sequence in the toxin to make it more selective for clinical purposes.