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Characterization of Wiskott^aldrich Syndrome(was)mutants Using Saccharomyces Cerevisiae Essay Preview: Characterization of Wiskott^aldrich Syndrome(was)mutants Using Saccharomyces Cerevisiae Report this essay Abstract Wiskott-Aldrich syndrome (WAS) is caused by alterations in the WAS protein (WASP), and 80% of the missense mutations are located in the WH1 domain, the region essential for interaction with the WASP-interacting protein (WIP). It.