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Progressive Multifocal LeukoencephalopathyEssay Preview: Progressive Multifocal LeukoencephalopathyReport this essayIntroductionCharacteristics of Disease:Progressive Multifocal Leukoencephalopathy is a rare and usually fatal disease that infects and kills oligodendrocytes in the white matter of the brain. Oligodendrocytes are a part of the central nervous system and are responsible for manufacturing the myelin that encloses and insulates some of the.