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Infectious Mononucleosis (mono) Essay Preview: Infectious Mononucleosis (mono) Report this essay Infectious mononucleosis is caused by the Epstein-Barr virus (EBV). It is a double stranded DNA virus indistinguishable from other members of the herpes virus group. It get its name from the mononuclear (single nucleus) cells. It is also known as the “kissing disease”, because.