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Prions and BseEssay Preview: Prions and BseReport this essayBovine Spongiform Encephalopathy (BSE), primarily known as Mad Cow Disease, was first detected in Great Britain in 1986. (1) Since it was first detected, there had been 181376 confirmed cases in the United Kingdom from a span of November 1986 to November 2002. (2) BSE is an.